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Use of the gastrointestinal drug reglan, and other generic drugs containing metoclopramide, can cause a disabling neurological syndrome known as tardive dyskinesia, which involves involuntary and repetitive movements that can be permanent.

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Do not use Reglan if you’ve ever had muscle movement problems after using metoclopramide or similar medicinesor if you’ve had a movement disorder called tardive dyskinesiaYou also should not use this medicine if you’ve had stomach or intestinal problemsa blockagebleedingor a hole or tearepilepsy or other seizure disorderor an adrenal gland tumorpheochromocytoma

For doses in excess of 10 mgReglan Injection should be diluted in 50 mL of a parenteral solution.

Do not use Reglan if you’ve ever had muscle movement problems after using metoclopramide or similar medicinesor if you’ve had a movement disorder called tardive dyskinesiaYou also should not use this medicine if you’ve had stomach or intestinal problemsa blockagebleedingor a hole or tearepilepsy or other seizure disorderor an adrenal gland tumorpheochromocytoma

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The risk of developing parkinsonian-like side effects increases with ascending doseGeriatric patients should receive the lowest dose of Reglan Injection that is effectiveIf parkinsonian-like symptoms develop in a geriatric patient receiving Reglan InjectionReglan Injection should generally be discontinued before initiating any specific anti-parkinsonian agentssee WARNINGS

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